Vivarium and Transgenics Core

Selected Publications

Preclincial therapeutics

Rodriguez WV, Woolliscroft MJ, Ebrahim AS, Forgey R, McGovren PJ, Endert G, Wagner A, Holewa D, Aboukameel A, Gill RD, Bisgaier CL, Messmann RA, Whitehead CE, Izbicka E, Streeper R, Wick MC, Stiegler G, Stein CA, Monsma D, Webb C, Sooch MP, Panzner S, Mohammad R, Goodwin NC, Al-Katib A. 2014. Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide. Cancer Chemother Pharmacol. 74(1):151-156 PubMed

Monsma DJ, Cherba DM, Richardson PJ, Vance S, Rangarajan S, Dylewski D, Eugster E, Scott SB, Beuschel NL, Davidson PJ, Axtell R, Mitchell D, Lester EP, Junewick JJ, Webb CP, Monks NR.  2014. Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.  Pediatr Blood Cancer 61(9):1570-1577. PubMed

Monsma DJ, Monks NR, Cherba DM, Dylewski D, Eugster E, Jahn H, Srikanth S, Scott SB, Richardson PJ, Everts RE, Ishkin A, Nikolsky Y, Resau JH, Sigler R, Nickoloff BJ, Webb CP. 2012. Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue. J Transl Med 10:125. PubMed

Phadke AP, Jay CM, Wang Z, Chen S, Liu S, Haddock C, Kumar P , Pappen BO, Rao DD, Templeton NS, Daniels EQ, Webb CP, Monsma DJ, Scott S, Dylewski D, Friedboes HB, Brunicardi FC, Senzer N, Maples PB, Nemunaitis J, Tong AW. 2011. In vivo safety and antitumor efficacy of bifunctional small hairpin RNAs specific for the human Stathmin 1 oncoprotein. DNA Cell Biol 30(9): 715-726. PubMed

Rao DD, Maples PB, Senzer N, Kumar P, Want Z, Pappen BO, Yu Y, Haddock C, Jay C, Phadke AP, Chen S, Kuhn J, Dylewski D, Scott S, Monsma DJ, Webb CP, Tong A, Shanahan D, Nemunaitis J. 2010. Enhanced target gene knockdown by a bifunctional shRNA: a novel approach of RNA interference. Cancer Gene Ther 17(11): 780-791. PubMed

Hostetter G, Kim SY, Savage S, Gooden GC, Barrett M, Zhang J, Alla L, Watanbe A, Einspahr J, Prasad A, Nickoloff BJ, Carpten J, Trent J, Alberts D, Bittner M. 2010. Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples. Nucleic Acids Res 38(2): e9. PubMed

Phadke AP, Chen S, Rao DD, Jay C, Wang ZH, Kumar P, Dylewski D, Scott S, Tong AW, Maples PB, Senzer NN, Monsma D, Webb C, Nemunaitis J. 2009. Safety studies of a Stathmin 1 bifunctional shRNA in murine xenograft of human osteosarcoma and a human colon cancer cell line.  Mol Ther 178: S114-S114.

Kuick R, Misek DE, Monsma DJ, Webb CP, Wang H, Peterson KJ, Pisano M, Omenn GS, Hanash SM. 2007. Discovery of cancer biomarkers through the use of mouse models. Cancer Lett 249(1): 40-48. PubMed

Creighton CJ, Bromberg-White JL, Misek DE, Monsma DJ, Brichory F, Kuick R, Giordano TJ, Gao W, Omenn GS, Webb CP, Hanash SM. 2005. Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Mol Cancer Res 3(3): 119-129. PubMed